In 2021, he was named Penn Presidential Professor at the University of Pennsylvania School of Veterinary Medicine,[6] and Associate Director of the PennVet Institute for Infectious and Zoonotic Disease (IIZD).

In 2021, he presented a review on the major inventions in the immunology of helminth infection made over the last decade, ranging from innate lymphoid cells to the emerging importance of neuroimmune connections.

[17] Herbert also contributed to a study led by Carla Rothlin at Yale that aimed to determine the role that genetic ablation of a receptor tyrosine kinase encoded byTyro3in mice or the functional neutralization of its ortholog in human dendritic cells, serves to play in terms of enhancing type 2 immunity.

[18] Additional research centered on discussing the implications of AMP-activated protein kinase (AMPK), highlights that myeloid-restricted AMPKα1 tends to promote host immunity and restrict IL-12/23p40-dependent lung injury resulted from hookworm infection.

[19] Some of Herbert's research is focused on determining the role served by intestinal epithelial cells in the process of worm expulsion through producing immunoregulatory cytokines and bioactive mediators that interfere with parasite chemosensory locomotion.

[21] In a later study, led by Nicole Maloney Belle, the Herbert lab pursued the importance of Trefoil factor proteins in the reparative functions of intestinal epithelial cells (IEC) in nutrient absorption, regeneration, and mucus secretion.

In a 2012 research study conducted on mice, they demonstrated the implications of TFF2 (trefoil factor 2), an epithelial cell-derived repair molecule, in terms of controlling lung injury caused by the hookworm parasite Nippostrongylus brasiliensis and for type 2 immunity after infection.

[23] His studies demonstrated that lung macrophages rely upon Trefoil factor 2 to promote epithelial proliferation following damage caused by sterile wounding, Nippostrongylus brasiliensis or Bleomycin sulfate.