De Bie is a surname of Dutch origin.
"De bie" (modern spelling "de bij") means "the bee", and the surname can be of metonymic occupational origin, e.g. a paternal ancestor may have been a bee-keeper.
Other origins could be an address ("from a house with a sign of a bee") or be metaphorical (e.g. a busy person).
[1] Variant spellings include De Bij, De Bije, De By, De Bye, DeBie, Debije and Debye.
People with this name include: