Anne de Guigné (25 April 1911 – 14 January 1922) was a young French girl who is being considered for sainthood by the Roman Catholic Church.

Anne's father was Count Jacques de Guigné, second lieutenant in the 13th Battalion, Chambéry of Chasseurs Alpins.

Anne's maternal great-grandmother, Louise de Bourbon, comtesse de Vierzon was the natural child of Ferdinand Duke de Berry, the second son of French King Charles X, making her a direct descendant of Louis XIII, XIV and XV as well; her maternal grandmother, Francoise Eulalie Marie Madeleine de Bourbon-Busset, was a direct descendant of the sixth son of King Louis IX of France, Robert, Count of Clermont.

On 29 July 1915 Anne's father died leading an attack against the Germans in World War I.

[citation needed] Anne began to have headaches due to spinal pain, but still did her work in school.