The once significant town was doomed by the Lieutenant-Governor Edgar Dewdney acquiring substantial land ownership at the site Pile-of-Bones, soon re-named Regina, and deeming it the capital of the North-West Territories (as then spelled), as early as 1883.

Bishop's Court and the diocesan administrative bureaucracy having been removed first to Indian Head in the 1890s and then Regina at the beginning of the twentieth century, pro-cathedral status was ultimately removed from St Peter's, Qu'Appelle and conferred on St Paul's, Regina in 1944: at that time the diocesan property at the corner of Broad Street and College Avenue was planned ultimately to contain a substantial cathedral, whose anticipated site is still outlined in caragana hedges and whose liturgical west front faced the intersection to the northwest.

By 1974 fiscal and demographic realities—Anglicans are a tiny minority of the population of southern Saskatchewan—had dispelled that fantasy and St Paul's was formally elevated to cathedral status.

The cathedral has intermittently been the home of impressive liturgy and music (see Donald M. Kendrick); latterly its worship has been infelicitously described as "high church meets happy clappy.

Of some historical interest is the ambitious cathedral site laid out diagonally at the corner of Broad Street and College Avenue, still clearly outlined in hedges.

With its 29 (or 30, depending on how one designates the Parishes of the British Columbia Central Interior, the former Diocese of Cariboo) it may be somewhat top-heavy with episcopacy given its small numbers outside Ontario and the Maritimes.

[6] By 1973 it was apparent that the diocese could never be self-supporting other than by alienating its only substantial real estate and that the original ambition to build a sizable cathedral in Regina could never be realised.

St Paul's was then formally upgraded to cathedral status and a satisfactory 2-manual Casavant Frères organ built under then-organist Donald M. Kendrick and Dean James Allan,[7] a gift of the Whitmore family of $20,000.

Donald M. Kendrick of Calgary, Alberta, subsequently conductor of the Bach-Elgar Choir in Hamilton, Ontario and of the faculty of California State University, Sacramento, was organist and choirmaster during the mid-1970s; during his tenure at St Paul's and the then-University of Saskatchewan, Regina Campus, St Paul's was the centre of liturgical music in Regina, and a generation of Canadian choral and keyboard musicians was trained and continue to contribute to Canadian and world music.

It was at Mr Kendrick's instance, with the enthusiastic support of Dean Allan and the financial underwriting by the Whitmore family, that the current small but fine Casavant Frères organ was installed in north transept of the cathedral in May 1974.