[2] In cinema, she stood out as Moema in Caramuru - A Invenção do Brasil, Judite in Boa Sorte and the title character in Bruna Surfistinha.

While playing in theatre, such as Sapatinhos Vermelhos, which earned her the nomination for the Coca-Cola Theater Award, in the category of Best Actress Breakthrough, television participated in the episodes "Tabu" and "Mamãe Coragem", Você Decide program, the children's school of Escolinha do Professor Raimundo, in celebration of Children's Day, both in 1992.

In 1995, she returned to Rede Globo, where she remains until the present day with exclusive contract of artist of the first step, and acted in her first novel of prime time, A Próxima Vítima.

In 1996, she played Barbara's spirited novel Vira-Lata, who for a good part of the plot pretends to be a boy, given the name Tatu.

In 2005, she played her first primetime character in America – Sol, a woman who tries to make a living in the United States, even if she is an illegal immigrant.

In 2008, she co-starred in the novel A Favorita, where she lived the ambitious and disguised recruiter Maria do Céu, a girl of humble origin who does not accept her condition and does everything to rise in life.

[6] Still in 2008 she made a nude rehearsal for RG Vogue, who chose the actress as the "favorite complete" and "sexiest woman in Brazilian TV".

[7] On March 4, 2010, Folha Online published an article regarding a complaint by the Brazilian Public Prosecutor's Office, accusing Deborah Secco and other 86 people for administrative impropriety.

[8] The complaint, upheld by the Rio de Janeiro state court, describes irregularities in Deborah Secco's participation in advertisements by the governments of Anthony and Rosinha Garotinho, with whom five of Deborah's family members would have been involved, according to the complaint, to appropriate irregularly public money.

According to the newspaper O Globo, the complaint indicates that Deborah Secco's bank accounts received at least 158 thousand reais in public resources diverted in a scheme commanded by her father.

[18] On December 6, the actress received another award, the personality of the year in dramaturgy, an event promoted by Editora Três, which was attended by President Dilma Rousseff as well.

[19] According to a note released by Veja magazine, Deborah Secco was the most cited Brazilian celebrity in the year 2011 by the press.

[22] That same year, she was inducted by Steven Spielberg to work in Hollywood, where she represented Brazil at the 40th AFI Life Achievement Awards, which honored actress Shirley MacLaine.

[23][24] In 2013 Deborah Secco recorded the feature film Boa Sorte, in which she gives life to the positive serum Judite.

[34] In 2015, she would live the protagonist Carolina in the novel Verdades Secretas of Walcyr Carrasco,[35] but during the recordings, she discovered her first pregnancy, fruit of the relationship with the present boyfriend, the Bahian Hugo Moura, consequently left the plot.

The serial, written by João Emanuel Carneiro, debuted in the first half of 2018 correcting O Outro Lado do Paraíso.

After two years living together, Deborah married Flores on June 6, 2009, in Itaipava, a mountain region of Rio de Janeiro, in a discreet ceremony.