These experiments provide the predatory animals with heightened intelligence, inadvertently causing the sharks to attack the underwater facilities and hunt the researchers that created them.

Director Renny Harlin had become well known for bringing stylish action sequences into his films, but he also was noted for pushing the boundaries of effects work.

For Deep Blue Sea, Harlin employed animatronics wizard Walt Conti and his company Edge Innovations (which previously worked on Anaconda), to create the most lifelike on-screen shark puppets at that point in time.

8 on the Top 20 Sellers for the week ended April 21, 2018 and being on-par with theatrical releases,[8][9] Deep Blue Sea 2 was panned by critics.

On an island research facility, Dr. Susan McAlester is conducting experiments to cure Alzheimer's disease, by harvesting the brain tissue of DNA-altered mako sharks.

[14][15] By May 2020, it was revealed that the film had finished production within the last year, with principal photography taking place in Cape Town of the Republic of South Africa.

[16][17][18][19] The plot centers around Dr. Emma Collins, who leads a team at a small island studying the effects of climate change on great white sharks.