The Delerme-Anduze House (Spanish: Casa Delerme-Anduze), also known as the Rosendo Delerme House (Casa Rosendo Delerme),[1] is a historic Spanish Creole vernacular house located in Isabel Segunda, the largest and main administrative and historic settlement of the island-municipality of Vieques, Puerto Rico.

[2] The house was built following the gallery-type French Caribbean vernacular tradition (known as Louisiana-style in the United States) during the 1850s by Augusto Neré Delerme, a wealthy French immigrant from Guadeloupe.

It was added to the National Register of Historic Places in 1994 as it is described as the finest example of French Creole house in Vieques and one of the few of its type remaining anywhere in the United States.

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