Founding several cultural and feminist clubs, Weber successfully navigated the Trujillo years, helping to gain both civil and political rights for women.

[1] Her paternal grandfather, Alfred von Weber, whose ancestry traced to Dresden, was a musician who had immigrated from Amsterdam to the Caribbean and married Pauline Sulié, a native Curaçaoan woman.

[2] When she was twelve years old, Weber entered the Liceo Núñez de Cáceres, graduating from her higher primary studies in 1914.

In 1923, she joined the first feminist organization in the country, also founded by Gómez, Central Committee of Dominican Feminists (Spanish: Comité Central Feminista Dominicano (CCFD)), the local arm of the International League of Iberian and Latin American Women (Spanish: La Liga Internacional de Mujeres Ibéricas e Hispanoamericanas).

She also lived in Paris, Switzerland and Vienna[4][6] and during this time added three more sons to the family, Enrique, Antonio and Salvador Coiscou Weber.

In 1931, the club reorganized as Dominican Feminist Action (Spanish: Acción Feminista Dominicana (AFD)) with Mejía serving as director general and Weber as the secretary-general.

[1][10] The following year, Mejía died and Weber ascended to the office of director general for the AFD, continuing to press for more rights.

[1] At the same time, in 1941, Weber and her son Rodolfo worked together to establish the Alpha & Omega Recreational Literary Club.

[1] In 1952, Alpha and Omega Club folded because of accusations by Trujillo that Rodolfo was plotting against the government and propagating communist doctrines.

Toward the end of the decade, her works moved toward abstract expressionism, using a broader range of colors incorporating bright white lights, celestial blues, lilac, orange and purple tones.

In 1969, she prepared her first solo show of 42 canvases, which was well received by reviewers, who praised her landscapes as pictorial and filled with intense emotion with a well-balanced sense of harmony and color.