The Delmenhorst–Hesepe railway is a single-track, non-electrified railway line from Delmenhorst to Hesepe, both in the German state of Lower Saxony.

The first section from Vechta to Lohne was opened in 1888 as part of the Ahlhorn–Vechta railway.

One year later on 1 November 1899 the section between Lohne and Neuenkirchen opened.

The services on the line have been operated by NordWestBahn since November 2000.

The current contract continues until December 2026.