Delucemine (NPS-1506) is a drug which acts as an NMDA antagonist and a serotonin reuptake inhibitor, and has neuroprotective effects.

[1][2] It was originally investigated for the treatment of stroke and in 2004 was studied as a potential antidepressant.

[3][4][5] The structure of delucemine is based on argiotoxin 636, a NMDA antagonist isolated from the venom of Argiope aurantia.

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