From his father's previous marriages, Demetrius had various paternal half siblings, who included king Antigonus II Gonatas, as well as Stratonice of Syria, princess and later Queen of the Seleucid Empire.
Among his maternal aunts were Queen Arsinoe II of Egypt and among his maternal uncles were Pharaoh Ptolemy II Philadelphus and Macedonian King Ptolemy Keraunos (Keraunos was Ptolemais’ full blooded brother).
She was Demetrius' niece through his paternal half sister Stratonice of Syria and her husband Antiochus I Soter of the Seleucid Empire.
Jealous of her husband's affair with her mother, Berenice argued with both of them and consented to the assassination of Demetrius, who died in Apama's arms.
The poem Coma Berenices by Greek poet Callimachus (lost, but known in a Latin translation or paraphrase by Catullus), apparently refers to her coup against Demetrius: "Let me remind you how stout-hearted you were even as a young girl: have you forgotten the brave deed by which you gained a royal marriage?"