Music can be typed in using a PC keyboard, taken from MIDI input, or played into a microphone plugged into a soundcard.

Denemo includes scripts to run music tests and practice exercises for educational purposes.

Denemo can output entire scores (including Table of Contents and Critical Commentary automatically generated from comments placed in the music) as well as excerpts in a number of formats, including: The program allows the user to place links in the music to original source manuscripts/prints (in PDF files) allowing cross-checking of transcriptions.

It also allows audio recordings to be linked to a notated score with synchronization via automatically detected note-onsets; the notated score and audio are played back simultaneously and can be slowed down in real time to listen for discrepancies.

However, everything can be accessed by mouse, and both one- and two- key keyboard shortcuts can be created easily by the user for the task at hand.