Denise O'Donoghue, OBE (born 13 April 1955, in Wembley) is a British television production company executive.
As a television producer, O'Donoghue has worked on shows such as the original British version of Whose Line is it Anyway?, and Have I Got News for You.
In 2003, O'Donoghue and Mulville, as the remaining co-founders of Hat Trick, were listed in The Observer as two of the 50 funniest people in Britain.
In 2006, she married Michael Holland, an oil shipping businessman, whose wife, Jane Attenborough (daughter of Richard Attenborough), their daughter Lucy, and his mother, Jane Holland, drowned in the tsunami in December 2004.
She was appointed an OBE for services to television in the New Year Honours list of 1999.