While a faculty member at Washington University School of Medicine, Choi was a key contributor to research on glutamate-mediated toxicity ("excitotoxicity") as a mechanism of neural injury in stroke and traumatic brain injury.
As a graduate student he demonstrated that benzodiazepines augment GABA-A receptor function,[1] which represents a seminal discovery in neuroscience.
[2] In the Spring of 2009, Choi taught an undergraduate course entitled "Neurofunction and Artificial Intelligence" for the Emory University Neuroscience & Behavioral Biology Program.
[3] Choi is currently the chair of the Department of Neurology at Renaissance School of Medicine at Stony Brook University as well as Director of the Neurosciences Institute.
He sits on the scientific advisory boards of several companies and foundations, including the Cure Alzheimer's Fund.