Denver Clarence Grigsby (March 25, 1901 – November 10, 1973) was an outfielder in Major League Baseball.

He played for the Chicago Cubs from 1923 to 1925, and as a starter on the 1924 Cubs.

Grigsby had a respectable career batting average of .289 with an on base percentage of .355 over a period of 199 MLB games.

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