The Outlaws had their inaugural game on May 20, 2006, versus the Chicago Machine at Sports Authority Field at Mile High.
It was played in front of a Major League Lacrosse record crowd of 13,167 (but was broken again later that year at another Denver home game which drew 15,981), where the Outlaws won 24–14.
In 2012, behind the strong veteran play of MLL MVP Brendan Mundorf and Defensive Player of the Year Lee Zink, Denver capped their regular season with a 15–13 victory over Chesapeake to finish the year with an 11–3 record, which represented the most wins in team history for a single season.
Unfortunately, in the title game versus Chesapeake, the Outlaws were unable to muster that same kind of comeback magic and fell to the Bayhawks 16–6, falling one win short of their first MLL Championship.
On August 23, the Outlaws defeated the top-seeded Rochester Rattlers 12–11 to win their first MLL Championship in the team's 9-year history, thanks to a go-ahead Drew Snider goal with 56 seconds remaining.
After trading John Grant Jr. to the Ohio Machine, they won their last six games of the regular season to be one of the seven teams in the league to finish 8–6.
[5] But the resilient Outlaws rattled off six straight victories ending with a 25-11 blowout of Boston at their annual Fourth of July game in front of 29,973 fans.
[6] The following week in Charleston, South Carolina, the Outlaws would face the Dallas Rattlers, who also swept them in the regular season, for the 2018 Steinfeld Cup.
Denver would use a 7–0 run in the second and third quarters, and a nine-point performance from Matt Kavanagh to defeat Dallas, 16-12 for their third championship in five years.
[9] The 2020 season was shortened due to the COVID-19 pandemic and quarantined at Navy-Marine Corps Memorial Stadium in Annapolis, home to the Chesapeake Bayhawks.
In a five-game regular season, the Outlaws stormed to a 4–0 start highlighted by an 18-6 throttling of the new Connecticut Hammerheads and a 13–12 overtime victory over the defending champion Bayhawks.
[11] The move created a unified outdoor lacrosse league that kept the PLL name and eliminated all home market teams.