It is served by trains operated by Deutsche Bahn (DB) and the Breisgau S-Bahn (BSB) and has a total of four platform tracks.

Denzlingen station was opened with the commissioning of the Offenburg–Freiburg section of the Rhine Valley Railway (Rheintalbahn) from Mannheim to Basel via Karlsruhe and Freiburg on 30 July 1845.

[4] Operation of the line, which was opened on 1 January 1875, was transferred to the Grand Duchy of Baden State Railways (Großherzoglich Badische Staatseisenbahnen) in 1887.

The position of the crossing can still be seen today (2018) from the corrugated edge on platform 2 opposite the station building.

The rather stately entrance building of Denzlingen station now houses a branch of a bakery chain on the ground floor.

However, Denzlingen station occasionally serves as a substitute stop during construction work around Freiburg Hauptbahnhof if long-distance trains have to use the freight bypass.