Murphy started three seasons at Klein Forest High School, located in Houston, Texas.
He earned second team All-District 15-5A honors in 2004 and was regarded among the top 50 receivers in the state of Texas.
His senior year he helped Klein Forest finish to a 12-2 record and 9-1 for a bi-district title.
In 2007, Murphy was named the Big 12 Conference Offensive Newcomer of the Year and earned honorable mention accolades as a receiver and punt returner from the league’s coaches.
On October 7, 2009, Murphy was signed by the Calgary Stampeders of the Canadian Football League.