The department shapes the two research profile areas "Cybersecurity (CYSEC)" and "Internet and Digitization (InDi)" of the university.

The beginnings of computer science, artificial intelligence and business informatics in Germany go back to the department.

The institute was concerned with automating computing using mechanical and electromechanical devices and developing machines that could be used to solve mathematical problems.

The Darmstadt Electronic Calculator (DERA), which was completed in 1959, was created with the help of the German Research Foundation (DFG).

Two decades before the invention of programming languages, algorithms were tested on the computing station and successfully used to process problems from industry.

The advisory board, which consisted mainly of representatives of universities and non-university research institutions, was responsible for the implementation of the programme.

At the seventh meeting of the advisory board on 15 November 1967, Karl Ganzhorn, who at the time was responsible for research and development at IBM Germany, signalled the problems of industry in finding skilled personnel.

The director of the Institute for Information Processing at TH Darmstadt, Piloty, pointed out that the German universities were responsible for training qualified personnel.

There was already another curriculum with the name "Diplom-Ingenieur Informatik (Mathematik)", which came from the Faculty of Mathematics and Physics and provided for a stronger emphasis on software engineering.

In the spring of 1969, Hartmut Wedekind and Robert Piloty had travelled through the USA together for several weeks to study the faculties of computer science there.

In 1968, Peter Mertens was appointed to the first chair in the German-speaking countries focusing on economic data processing at the Johannes Kepler University Linz.

In the same year, Hartmut Wedekind, former systems consultant at IBM Germany, represented the Chair of Business Administration at TH Darmstadt for the first time.

He built up the necessary institutions, conferences and scientific journals and provided the necessary research programmes to establish the field of artificial intelligence.

The most outstanding scientific project was the National Priority Program Deduction, funded by the German Research Foundation (DFG).

[4] By 2017, twenty-five of his doctoral students or staff had become professors, so that the majority of today's German AI researchers are graduates of TU Darmstadt.

For his achievements he was honored by the Gesellschaft für Informatik as one of the ten influential minds in German AI history.

[5][6][7] The Centre for Cognitive Science (CCS) was founded at TU Darmstadt by Constantin Rothkopf, Professor of Psychology of Information Processing.

[9][10] In 2019, the TU Darmstadt was selected as a founding location of ELLIS with the aim of establishing a top AI research institute.

The European Center for Security and Privacy by Design (EC SPRIDE) was founded in 2011 as a result of the efforts of Buchmann and Waidner.

[15][16] In the same year, the German Research Foundation established the Graduate School for Privacy and Trust for Mobile Users on the initiative of Max Mühlhäuser.

One year later, the Federal Ministry of Finance decided to make the Darmstadt region an outstanding location for the digital transformation of the economy.

In 1973, the DRZ merged with other research institutions in this field to form the Gesellschaft für Mathematik und Datenverarbeitung (GMD).

The founding director was Claudia Eckert, who was also Professor for Information Security at the Technische Universität Darmstadt.

[22] In 1975, José Luis Encarnação founded the Research Group Graphic Interactive Systems (GRIS) at the Department of Computer Science of the Technische Hochschule Darmstadt.

Argonaut is a variant of Taurob tracker and the first fully autonomous, mobile inspection robot for oil and gas plants.

[30][31] In 2018, Hector competed at the World Robot Summit in Tokyo in the category "Plant Disaster Prevention Challenge" and won 1st place.