The club is based in the townland of Derrytresk near Clonoe in County Tyrone, Northern Ireland.

Although one of the smallest clubs in the county, with a catchment area of about 60 houses, Derrytresk won the 2011 Tyrone JFC, defeating Killeeshil 0-15 to 0-9.

They went on to win the Ulster Junior Club Football Championship, defeating Monaghan's Cremartin 2-5 to 0-10.

[1] They won their All-Ireland semi-final against Kerry's Dromid Pearses (1-10 to 7 points), but narrowly lost the final in February 2012 to Naomh Pádraig of Galway.

[2] The club has at times played in the Senior Championship, reaching the final in 1949 when they were defeated by An Charraig Mhór.