[1] Next to the street is Odesa's first park, which was built shortly after the foundation of the city in 1803 by the De Ribas brothers, Joseph and Felix (Josep and Fèlix).

During the first years of Bolshevik rule (1920–1938) it was named after the German socialist Ferdinand Lassalle.

[3] Derybasivska street was closed to car traffic and turned into a pedestrian zone in the spring of 1984.

Prior to that, it was used not only by cars, but also by the city trolleybuses of route 1 and 2, which were moved to the neighbouring streets after replanning.

Every year on first of April the Humorina procession goes the whole length of Derybasivska Street, which is packed with tens of thousands of onlookers and participants dressed in funny costumes.