Camille, the oldest child, expects to find a safe haven by the coast, and she leads several younger children through the land, where they must avoid bloodthirsty soldiers who mistake them for zombies.

[7] William Harrison of DVD Talk rated it 1/5 stars and wrote, "Repetitive, confusing and boring, Descendents is a waste of time.

[9] Devon Ashby of CraveOnline rated it 2/10 stars and wrote, "Descendents' awkwardly unconventional execution and overreliance on child performers gives it an unfinished, diffuse quality that tragically disappoints rather than inspiring.

"[10] Marc Patterson of Brutal As Hell called it "smartly made and quite stunning to watch" but said that it eventually becomes boring, unsubtle, and superficial.

[11] Peter Dendle wrote, "Despite its limitations, the movie uniquely situates the infected against an unforgettable, anemic world, one saturated throughout with sickness and veiled in pale ochre.