Desglymidodrine (developmental code name ST-1059) is the active metabolite of the prodrug antihypotensive agent midodrine.

[1][2][3] Desglymidodrine is formed from midodrine via deglycination.

[1][2][3] Desglymidodrine, also known as 3,6-dimethoxy-β-hydroxy-2-phenylethylamine, is a substituted phenethylamine derivative.

[6][7] The predicted log P of desglymidodrine ranges from -0.01 to 0.15.

[4][5] An analogue of desglymidodrine is dimetofrine (3,5-dimethoxy-4,β-dihydroxy-N-methylphenethylamine).