[6] Common side effects include low blood sugar, allergic reactions, pain at the site of injection, and weight gain.

With respect to blood sugar management, it appears to work better than NPH insulin, however this finding was inconsistent across included and previous studies.

[12] Common side effects include low blood sugar, allergic reactions, pain at the site of injection, and weight gain.

[13] In June 2009, the US Food and Drug Administration (FDA) issued a public health advisory for insulin determir after learning that 129,000 stolen vials reappeared and were being sold in the U.S. market.

The FDA warned that the stolen vials "may not have been stored and handled properly and may be dangerous for patients to use."