Diana was launched in 1799 at Topsham as a West Indiaman.

As Marquis of Lansdown was returning to England from Jamaica, on 23 June 1802 she sighted a large vessel wrecked on the west end of the Isle of Pines.

A sloop from the Grand Caymanes reported that the wrecked vessel was Diana, Williams, master, which had been sailing from Jamaica to Liverpool.

A wrecker had visited Diana and salvaged 100 pipes of Madeira wine, which she had taken to Caymanes.

Captain Williams had died after leaving Jamaica.