Her laboratory focuses on epigenetic regulation by the BAF (SWI/SNF) chromatin remodeling complexes in diverse physiological processes including development, immunity, and diseases such as cancer.

Hargreaves obtained her PhD in Immunology at Yale University where she studied in the lab of Ruslan Medzhitov, a leader in the field of innate immunity and pathogen recognition.

[4] Hargreaves was appointed professorship at the Salk Institute for Biological Studies in 2015 where she continues her focus on the chromatin remodelling complex BAF.

[5] Her lab has recently discovered a specific subunit of BAF that is responsible for maintaining cellular pluripotency, an unbiased differentiation state.

[7] Hargreaves also investigates epigenetic chromatin remodelling with a goal of identifying therapeutic targets that harness the immune system to defend against tumors.