O'Keeffe had his first success at adult level in 2012 when he won a Wexford SFC medal following St Anne's Rathangan 2-14 to 0-08 defeat of Castletown in the final.
[10] O'Keeffe made his senior team debut in February 2012 when he lined out at centre-forward in a 3-18 to 2-15 National League defeat by Antrim.
[11] He claimed his first senior silverware in 2018 when Wexford won the Walsh Cup after a free-taking shoot-out defeat of Kilkenny.
[16][17] O'Keeffe works as a secondary school teacher in St. Peter's College in Dunboyne, County Meath.
[18] His father-in-law, Jarlath Burns, is an Ulster SFC-winner with Armagh who became President of the Gaelic Athletic Association in 2024.