She earned recognition starring as Katya Kinski in the soap opera Neighbours (2005–2007) and as Sierra in Joss Whedon's science fiction drama series Dollhouse (2009–2010).

Lachman has appeared in numerous films, such as Aquamarine (2006), Bled (2009), Lust for Love (2014), Too Late (2015), Bad Therapy (2020), Joe Baby (2024), and Kingdom of the Planet of the Apes (2024).

In the interview, she explained that she was in Los Angeles to advance her acting career, but said she would love to work in the UK and Australia.

On 26 March 2008, it was announced that Lachman would portray Sierra in the television series Dollhouse, created by Joss Whedon.

[12] Lachman also made a brief appearance in the web-series The Guild during Season 5, episode 8 as a party guest during a gaming convention.

In 2012, it was announced Lachman would be joining the Shawn Ryan–driven pilot Last Resort for ABC,[13] and she subsequently appeared as a main character during the show's 13-episode run.

The initial goal was to raise US$70,000; however, when the deadline was reached on 11 November 2011 more than 1,500 people had pledged money, with a final figure of US$101,030.

On 11 June 2015, a new movie called Too Late, starring Lachman, was released during the Los Angeles Film Festival.

On 22 October 2015, it was announced that Lachman landed a recurring role on the third season of Michael Bay's action-adventure TNT series The Last Ship.

[18] She starred as Reileen Kawahara in Netflix's original television series, Altered Carbon, an adaptation of the 2002 novel of the same name by Richard K. Morgan.