Albinoni's music (now lost) was set to Pietro Metastasio's libretto, Didone abbandonata, which was in turn based on the story of Dido and Aeneas from the fourth book of Virgil's Aeneid.

However, for the libretto's presentation in Venice, Giovanni Orsato, the impresario of the Teatro San Cassiano, commissioned his fellow Venetian, Tomaso Albinoni, to compose a completely new setting.

He intended it as a showcase for her, and according to contemporary accounts, Bulgarelli had considerable influence on the work, especially in shaping Dido's scenes of jealousy in act 2.

[5] Marianna Bulgarelli and her Aeneas, Nicolò Grimaldi, reprised their roles on 10 May 1725 in Reggio Emilia for the premiere of Nicola Porpora's setting of the Didone libretto.

Markstrom suggests that she was probably also present in Rome to coach the castrato "Farfallino" who sang the title role in Leonardo Vinci's 1726 setting of the libretto.