Although he never knew his maternal grandfather, Otto Boneta, a songwriter and psychiatrist, Diego credits him with his musical talents.

[4] In 2010, at the age of 20 years, he appeared in the TV series Pretty Little Liars as Alex Santiago and in 90210 as Javier Luna which was "practically me with a different name" where he could sing and compose, mainly "Siempre tú" which came out at the end of the second season and the beginning of the third.

[4][8] His first film came in 2011 as Tyler Adams in the teen flick Mean Girls 2 opposite Meaghan Martin and Jennifer Stone.

[4] As he shot into the spotlight he became the cover model of TROIX magazine's 'March Men Madness' 2011 issue, introducing him as "Prince Charming".

[9] His big Hollywood break came when he starred in Adam Shankman's film adaptation of the hit Broadway musical Rock of Ages alongside Tom Cruise and Julianne Hough.

He played Drew Boley, a young upstart in Los Angeles in the late 1980s with dreams of becoming a rock star.

Of Boneta's audition, Shankman called him the "next big thing" and compared him to Zac Efron, Channing Tatum, and Liam Hemsworth.

Between September and December 2015, he starred in Ryan Murphy's comedy-horror series Scream Queens for the Fox network.

The show featured an all-star cast including Ariana Grande, Keke Palmer, Nick Jonas, Emma Roberts, Jamie Lee Curtis and Lea Michele.

[citation needed] His songs were synchronized in the telenovela Rebelde and, once finished, he went on an international tour with Mexican pop group RBD as a guest.