He joined the Fundación Contemporánea, a think tank,[1] and was brought on by economist Aldo Abraham as a member of his Exante consulting firm.

[1] Bossio's wife had worked as an adviser to Senator Cristina Fernández de Kirchner before the latter's election as President of Argentina in 2007,[1] and was subsequently appointed Adjunct Director of SIGEN, the federal comptroller's agency.

Bossio's appointment as director of ANSES, which controls nearly a third of the national budget, prompted her resignation, however.

[4] Bossio's tenure at ANSES coincided with a number of significant new initiatives at the social insurance bureau.

He oversaw implementation of the Universal Childhood Entitlement, a program fostering vaccination and higher school enrollment among the 30% of children living in poverty;[5][6] as well as Conectar Igualdad, which purchased 3 million netbooks for secondary school students and teachers;[7] and an initiative announced in April 2011 to include ANSES members in the Board of Directors of all 42 companies on the Buenos Aires Stock Exchange in which it holds a significant stake.