Additionally he is the author of The Genealogical Discourse of the Ortizes of Seville and of the work Posterity of Juan de Céspedes, Trece and Commander of the Order of Santiago Monastery.

The best-known work is Ecclesiastical and Secular Annals of the very Noble and very Loyal City of Seville, Metropolis of Andalusia.

The book was edited by Juan García Infanzón, at the Imprenta Real, Madrid in 1677, which consists of 823 pages, dedicated to Juan Francisco de la Cerda, VIII Duke of Medinaceli, Adelantado and Notary of Andalusia, Sheriff Major of Seville, descendant of the holy king Ferdinand III of Castile and León, conqueror of Seville in 1248.

In his criticism, José Pellicer de Tovar, Knight of the Order of Santiago, the king's senior chronicler Felipe IV, affirms that Ortiz de Zúñiga carried out his work “having seen and examined with all diligence, not only the Stories of Spain, but the monuments of the Archives of the Holy Metropolitan Church and the Parishes and Regulars and its enlightened Secular Cabildo.

Affirmation that is also made by Juan Lucas Cortés, of the King's Council and his mayor of House and Court: “In these Annals you will see all the memorable events that occurred in that city in the year and time that it touches them and many particular news, and so far not observed of some other, regarding the Universal History of Spain and of our kings, due to the diligence and work of the author, who did not excuse any, seeing and recognizing all the archives of the church, city, other communities and individuals and also of scriptures and privileges of them, with which in addition to the security and truth with that they are adjusted…” He also wrote and had printed Posteriority of Juan de Céspedes, Trece and Commander of the Monastery in the Order of Santiago and began to write his work Theater Genealogical of the Céspedes of Seville.