Murphy has served as head coach of the Boston Blades, with whom she won two Clarkson Cups, and Kunlun Red Star WIH in the Canadian Women's Hockey League (CWHL).

Prior to joining the Blades, she was the head coach of the Brown Bears women's ice hockey program.

Murphy was inducted in the Scholar-Athlete Hall of Fame at the Institute for International Sport in South Kingstown, Rhode Island.

[7] Brown ultimately offered the position to Brendan Whittet, who had no history of NCAA head coaching experience at the time, over Murphy.

[10] As a side note, Amanda Asay, who competed for Murphy from 2006–09,[11] was a participant in the inaugural women's baseball tournament at the 2015 Pan American Games.

Serving as the head coach of the Kunlun Red Star WIH franchise, one of two expansion teams in China, the club featured goaltender Noora Räty and forward Kelli Stack, who played for Murphy with the Blades.

By season's end, the Red Star qualified for the 2018 Clarkson Cup championship game, which they lost to the Markham Thunder.

[15] On April 22, 2020, Murphy was named president of the National Women's Hockey League's (NWHL) first Canadian expansion franchise, the Toronto Six.

[17] With a coaching staff that included Lisa Haley, Murphy led the Six to a first place finish during the 2020–21 NWHL season, highlighted by a four-game winning streak.

In addition to Murphy and Kirby, the inaugural Play It Forward Sport Foundation's leadership group comprised Valarie Gelb, Debbie McKay, John Mayers, and Olympic silver medalist and Clarkson Cup champion Molly Schaus.

[25] As of 2021, the foundation's advisory board includes Gelb, Kirby, McKay, Murphy, and two additions in former Cornell Big Red captain Sue Fulshaw and Eyekonz Field Hockey and Lacrosse founder Jazmine A Smith.

When Murphy accepted the head coaching position with Kunlun Red Star WIH for the 2017–18 CWHL season, operation of the UWLX was transferred entirely to 3d Lacrosse.

During a staff reduction at Data General, she accepted a buy out offer and began studying at the University of Rhode Island to become a physical education teacher before joining the Brown Bears women's program as an assistant coach in 1987.