[2] In 2016, he was part of the Artistic Alliance for Justice campaign video encouraging black people to vote in the 2016 United States presidential election.

[4] After playing the young fisherman who catches Tyra Banks in a McDonald's commercial in 1996, Talton had his first acting role in 1998, portraying the kid in L.A.

[7] He described his character as a fun person who always wanted to join the glee club but, as a member of the football team, felt this was unacceptable until quarterback Finn Hudson (Cory Monteith) did.

[20] Talton starred as Kendall, a gay black man, in the Lena Waithe-produced television pilot Bros, which was picked up for development by HBO in 2014.

[32] For the company, he is executive producer and director of the 2022 Allblk show À la carte with Meagan Good.

The show is Talton's directorial debut, and he has said that "[he] wanted to direct Á La Carte because it's a good story.