[1] On Tuesday 29 April 2014 – the Feast of St Catherine of Siena – Pope Francis appointed Joseph Toal as the fifth bishop of Motherwell.

The following is a list of the Bishops of Motherwell:[1] In 2021, there were 60 parishes in the diocese served by 79 priests (including religious) and 16 deacons.

Johny Vettickal Abraham is chaplain to the Syro-Malabar community and is resident at St John Ogilvie, Blantyre.

Cardinal Thomas Winning, a priest of the diocese born in Wishaw, was Archbishop of Glasgow from 1974 until his death in 2001.

Maurice Taylor, a priest of the diocese was the Bishop of Galloway and served as Scotland's representative on the board of International Commission on English in the Liturgy.

On Wednesday 24 July 2013, Leo Cushley, a priest of the diocese of Motherwell, was appointed the Archbishop of St Andrew's & Edinburgh.

John Farrell, retired priest of the Diocese of Motherwell,[6] the last Head teacher at St Ninian's Falkland, Fife, was sentenced to five years imprisonment.

Farrell and Kelly were members of the Irish Christian Brothers when the crimes were committed at the school which closed in 1983.