Among his most important musical influences Diodato mentioned Pink Floyd, Fabrizio De André, Luigi Tenco, Domenico Modugno and Radiohead.

[3] He has released five studio albums, E forse sono pazzo (LeNarcisse/Goodfellas),[4] A ritrovar bellezza (LeNarcisse/RCA/SonyMusic),[5] Cosa siamo diventati, Che vita meravigliosa and Così speciale.

[8] In 2018, he participated with the song "Adesso", featuring Roy Paci, in the Sanremo Music Festival 2018, placing eighth in the grand final.

[12] As the winner of the Festival, Diodato was also designated as the Italian representative at the Eurovision Song Contest 2020, however the event was cancelled due to the COVID-19 pandemic.

[14] On 9 May 2020, he won the David di Donatello for the best original song with "Che vita meravigliosa", used as the soundtrack of the film The Goddess of Fortune, directed by Ferzan Özpetek.