The Diodotid dynasty was a Hellenistic dynasty founded by Seleucid viceroy Diodotus I Soter[1][2] c. 255 BC, ruling the far-eastern Kingdom of Bactria.

The Diodotids were the first independent Greek kings to rule in Bactria.

Antiochus Nicator, a proposed Greco-Bactrian King c. 230s BC, would have belonged to the Diodotid dynasty (his existence as a distinct Greco-Bactrian ruler is controversial and his coins may have represented Seleucid authority).

[5] Diodotus II Theos was the last Diodotid ruler of Bactria.

His reign was marked for his controversial alliance with the Parthians against the Seleucid Empire.