[2] After midnight on Monday March 23, 1998, Amy and her younger brother Brad headed to the ship's nightclub to go dancing.

The ship's door lock records show that Brad had entered his cabin at around 3:35 am, and Amy soon followed five minutes later.

Amy's father Ron awoke around 6:00 a.m. to check on his daughter only to find her missing from the balcony she had slept on earlier.

When authorities were alerted that Amy was missing, the Netherlands Antilles Coast Guard conducted a four-day search in the surrounding waters and along the cruise lines to no result.

As well as this program, the case has been presented on Dr. Phil in a segment entitled The Search for Natalee: Amy Bradley, and also on America's Most Wanted.

The ship's computerized door lock system recorded that Brad returned to the cabin at 3:35 a.m. where Amy followed five minutes later.

Brad reported that he and his sister sat on the suite's balcony and talked before he went to sleep while Amy stayed awake for a while longer before she fell asleep shortly after.

"[11] After Ron searched the common areas of the cruise, he woke up the rest of the family and told them Amy was missing at 6:30 am.

The delay that the crew put on the search and investigation of the disappearance has been said to have led to lowering the chance of finding Amy by ignoring the Bradley family's advice and allowing the passengers to disembark.

However, this speculation was soon discredited as Amy was known to be a strong swimmer and her body was never found in the waters as well as no evidence of foul play.

[2][10][9][11] On the morning of the disappearance, two passengers told Ron that they saw a woman matching Amy's description taking an elevator to the ship's deck with cigarettes and a lighter.

[10] Another witness was a cab driver who stated that a woman matching Amy's description approached him and said she urgently needed a phone.

[10] In August 1998, a Canadian computer engineer claimed to have seen Amy walking down with two men on a beach in Curaçao, five months after the disappearance was made public.

He stated she told him that "her name was Amy Bradley and [she] begged him for help", explaining that she was held against her will and not allowed to leave[11][14] and did not report the incident earlier as he feared for his career in the Navy having been in a brothel.

[15] Frank told the family that he was a former US Army Special officer with a team of experienced soldiers who might be able to rescue Amy.

[15] Jones had claimed that his team had seen Amy being held by heavily armed Colombian personnel in a housing complex surrounded by barbed wire.

An image of a young woman resembling Bradley that was emailed to her parents was shown on the program and it suggests that she might have been sold into sexual slavery.

[1][18] Amy Lynn Bradley was declared legally dead on March 24, 2010, twelve years after the disappearance with no witnesses and no body found.

[19] There are several theories in regard to the disappearance of Amy Lynn Bradley, including one that she was kidnapped and sold into the illegal human trafficking industry in the Caribbean.