It is divided into two segments; one travels through the neighborhood of Ditmars, located within Astoria, and the other acts as a service road for the Grand Central Parkway near LaGuardia Airport in East Elmhurst.

The road continues to the east until it reaches the western edge of LaGuardia Airport, terminating at an intersection with 81st Street, north of Bowery Bay Boulevard and near Marine Air Terminal.

Now taking a more southern direction, Ditmars continues east along the Grand Central and merges with an exit 8 offramp.

The doctor, who died in 1860 at age 90, was held in high esteem by the community.

[2] Later, Steinway and Sons, the piano manufacturer, had a final assembly factory on Ditmars Boulevard until the 1960s.