[23] After setting a PB of 20.66 s in the semifinals at the 2014 World Junior Championships, he went on to win the silver medal in a windy 20.25 s behind Trentavis Friday of the US.

Oduduru ran a PB of 20.45 s into a headwind of 1.2 m/s to win the silver medal behind Ivorian sprinter, Hua Wilfried Koffi.

He set a personal best in the 60-meter dash at the 2019 Big 12 Indoor Championships, running 6.52 seconds for the distance to win the regional title.

[31][32] At the 2019 NCAA Division I Indoor Track and Field Championships he won the 200 m title and placed seventh in the 60 m final.

At the Big 12 Outdoor Championships, he won the 100 m in 9.99 seconds, having broken the 10-second barrier for the first time at the earlier Michael Johnson Invitational meet.

At the 2019 NCAA Division I Outdoor Track and Field Championships, he won a sprint double in the 100 m and 200 m, as well as taking third in the 4 × 100 m relay.

[33] Oduduru made his debut on the 2019 IAAF Diamond League circuit at the 2019 Herculis meet, but finished in last place.

[8] On February 9, 2023, Athletics Integrity Unit announced that Oduduru had been provisionally suspended for possession/use or attempted use of a prohibited substance (two potential Anti-Doping Rule Violations) in connection with the case of Blessing Okagbare, his compatriot banned for 11 years in 2022.