Djibouti competed at the 2018 Summer Youth Olympics in Buenos Aires, Argentina from 6 October to 18 October 2018.

Djibouti qualified 5 competitors for the games.

[1] Djibouti qualified 3 male athletes to compete in athletics at the games.

Djibouti qualified one female competitor for the games.

Djibouti qualified one female competitor in taekwondo.