In 1870, Sinodi-Popov entered the St. Petersburg Academy of Arts, where the amateur artist acquired good practical skills, but he had to interrupt his studies because he was suffering from epilepsy.
In late 1870s, the artist returned to his home city of Taganrog, continued his art studies and painted a lot.
The portrait of the artist Seraphima Blonskaya goes beyond the boundaries of its genre and transforms into a portrait-painting.
Sinodi-Popov exhibited in Europe and his name became well-known, bringing new orders and fans.
But with his illness progressing, the artist went for medical treatment to Rome and later Paris, where he died.