The single was officially released to radio the week of June 12, 2007.

In an interview with BET, Ne-Yo said that "Do You" is the second part to his song "So Sick" from his debut album, In My Own Words.

The version with Utada was included on the Ne-Yo: The Collection Japanese compilation.

She's then shown on a couch kissing her new boyfriend and lying on his lap, at the same time distant.

At the end she imagines herself reuniting with Ne-Yo, picturing them kissing, hugging, and caressing.