The protagonist is Joji Kano (加納 錠治, Kanō Jōji), a detective employed by the Tokyo Metropolitan Police Department's special crimes division, which handles serious criminal cases.

At the beginning of the manga, the only members of the Special Crimes Division were Kano himself and Superintendent Hiroshi Nishitani (西谷 博, Nishitani Hiroshi), but they would gradually be joined by additional members such as Detective Tetsuji Miyatake (宮武 鉄二, Tetsuji Miyatake), a gang specialist who was transferred to Shinjuku from Osaka; female detective Ryuko Mimori (三森 竜子, Mimori Ryūko); and from the United States, female detective Judy Terao (ジュディー寺尾).

[1] When Doberman Deka was chosen to end serialization in a few months due to low rankings in the Weekly Shōnen Jump reader surveys, rookie Kazuhiko Torishima was assigned as its editor.

Believing that Shinji Hiramatsu was good at action but bad at drawing women, Torishima gave him an issue of the actor and idol magazine Myojo and told him to model the face of a new policewoman character after that of the most popular idol at the time, Ikue Sakakibara.

Other than the main character Jōji Kanō (portrayed by Toshio Kurasawa), very few elements from the manga were adapted to the series.