The special was a series of comedy vignettes wrapped around the horror film Universal's House of Frankenstein.
Each week Doctor Madblood's Movie presented a film from the Universal 77 Horror Hits package.
Comedy vignettes were shown before and after the film and before and after each commercial break, featuring Doctor Madblood (a fictional retired mad scientist from Pungo, Virginia) and various other characters.
In 1989, Doctor Madblood's Movie returned to weekly television in Tidewater on the local Fox affiliate WTVZ-TV.
In the fall of 2002, Doctor Madblood moved into a weekly prime-time slot on WSKY-TV, which broadcast in the Tidewater (now known as Hampton Roads) market on cable channel four.