[1] The series follows directly from its predecessor Doctor at Large and depicts the former medical students now working as staff doctors at their alma mater St. Swithin's.

It was produced by London Weekend Television and broadcast on ITV during 1972 and 1973.

[2] Barry Evans, who starred in the first two series, did not return for this series, with the result that Robin Nedwell as Dr Duncan Waring became the central character of this and all remaining series in the franchise.

[3] Ratings for this series were high and featured regularly in the top 10 programmes on ITV.

Writers for the Doctor in Charge episodes were David Askey, Graham Chapman, Graeme Garden, George Layton, Jonathan Lynn, Bernard McKenna, Bill Oddie, Phil Redmond and Gail Renard.