It is a spa town known for its thermal baths established in 1658 by the Counts of Auersperg.

Dolenjske Toplice was attested in historical sources as Topliz in 1228 and Toplicz in 1328.

[4] The parish church in the settlement is dedicated to Saint Anne and belongs to the Roman Catholic Diocese of Novo Mesto.

The village lies on several tectonic faults, where water can penetrate deep into the crust and heat up.

Today there is a spa built around these warm springs, which is the biggest business in the settlement.