Domenico Cubelles (died 22 November 1566) was a Spanish Roman Catholic prelate who served as Bishop of Malta from 1541 till his death in 1566.

[2] On 21 October 1561 Pope Pius IV established the Roman Inquisition in Malta and Cubelles was appointed as the first Inquisitor of Malta by the bull "Licet ab Initio" on 15 July 1562.

[3][4] Cubelles also served as bishop during the Great Siege of Malta of 1565.

Bishop Cubelles dies on 22 November 1566.

This article about a Spanish Catholic bishop or archbishop is a stub.