Domenico de' Domenichi or Domenico de Dominicis (died 1478) was a Roman Catholic prelate who served as Bishop of Brescia (1464–1478)[1] and Bishop of Torcello (1448–1464).

[2] On 20 February 1448, Domenico de Dominicis was appointed during the papacy of Pope Nicholas V as Bishop of Torcello.

[2][3] On 14 November 1464, he was appointed during the papacy of Pope Paul II as Bishop of Brescia.

[1][3] He served as Bishop of Brescia until his death in 1478.

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