[3] Shortly after the accession of Phocas, in 603, the younger Domentziolus was raised to the titles of vir gloriosissimus, patricius and curopalates.
Phocas's elevation to the throne had been recognized by neither the Sassanid Persian shah Khosrau II, nor by Narses, the Byzantine governor of the province of Mesopotamia.
[9] With the Byzantine forces at the Persian front having already suffered heavy casualties in previous confrontations, Domentziolus was unable to oppose the Sassanid raids during 605.
Phocas had concluded peace treaties with the Lombards and Avars in an attempt to secure control of his provinces in the Italian Peninsula and the Balkans.
But this policy had backfired with the undermanned Balkans facing a Slavic invasion, notably endangering Thessalonica.
[8] While one Persian force, under Shahrbaraz, was able to secure control of Amida, Domentziolus concentrated his efforts on a second one under Shahin Vahmanzadegan.
He was heavily defeated in the vicinity of Theodosiopolis (modern Erzurum), and the Persians were able to recover most of Persarmenia, which had been ceded to Byzantium in 591.
Domentziolus's forces were bypassed, while another kinsman of Phocas, called Sergius, attempted to face the invaders and was killed in combat.
In Thessalonica and various towns of Anatolia and Syria, the Blues and Greens were settling their differences with open conflict.
Having secured control of Egypt, they proceeded to invade Syria and Cyprus while a large fleet under Heraclius the Younger, a son of the exarch, set sail for Constantinople.
Priscus, the commander of the Excubitors, chose the moment to reveal his allegiance to Heraclius, having apparently secretly conspired for some time.
[1] Elizabeth Dawes summarizes the tale given as following: "Domnitziolus, patrician and curopalates, asks Theodore to visit him in Arcadianae.
Then the Saint laying her on the ground Put his foot on her neck, turned his eyes to the east and uttered a silent prayer.